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Source: Journal of Thoracic Disease

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Total 1925 results found since Jan 2013.

Effectiveness and safety of the ABSORB bioresorbable vascular scaffold for the treatment of coronary artery disease: systematic review and meta-analysis of randomized clinical trials.
CONCLUSIONS: The implantation of BVS is associated with an increased risk of device thrombosis, ischemia-driven target lesion revascularization and target vessel MI. If longer follow-up or different implantation technique may change these findings should be addressed in future trials. PMID: 28894594 [PubMed]
Source: Journal of Thoracic Disease - September 14, 2017 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The role of cyclooxygenase-2 in the protection against apoptosis in vascular endothelial cells induced by cigarette smoking.
CONCLUSIONS: Endothelial cell apoptosis and the expression of COX-2 protein were increased in both COPD patients and CSE-induced vascular endothelial cells. Of interest, it seems that the COX-2 probably had a protective role against the apoptosis in the vascular endothelial cells induced by cigarette smoking. PMID: 28203404 [PubMed - in process]
Source: Journal of Thoracic Disease - February 18, 2017 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Established vascular effects of continuous positive airway pressure therapy in patients with obstructive sleep apnoea-an update.
Authors: Wons AM, Kohler M Abstract The aim of this review was to summarize the current data from randomised controlled trials (RCTs) on vascular effects of continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnoea (OSA). There is good evidence from RCTs that CPAP lowers blood pressure (BP) to a clinically significant amount. The effect seems to be dependent on the hours of nightly CPAP usage. Data from RCTs have also proven a beneficial effect of CPAP on measures of vascular function such as endothelial function and arterial stiffness. However, there is still a lack of evidence f...
Source: Journal of Thoracic Disease - June 26, 2015 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Vascular access for extracorporeal life support: tips and tricks.
The objective of this review is to describe the rational of the different ECLS techniques used in thoracic surgery and lung transplantation (LTx) with a specific attention to the vascular access. Venovenous extracorporeal membrane oxygenation (VV ECMO) is the most common ECLS technique used in thoracic surgery and represents the best strategy to support the lung function. VV ECMO needs peripheral vascular access. The selection between his double-site or single-site configuration should be decided according the level of O2 requirements, the nosological context, and the interest to perform an ECLS ambulatory strategy. Venoar...
Source: Journal of Thoracic Disease - May 21, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Acute respiratory distress syndrome caused by Mycoplasma pneumoniae without elevated pulmonary vascular permeability: a case report.
We report a case of ARDS caused by Mycoplasma pneumoniae without elevated pulmonary vascular permeability, which was successfully treated using low-dose short-term hydrocortisone, suggesting that pulmonary infiltration in ARDS caused by Mycoplasma pneumoniae does not match the criteria of permeability edema observed in typical ARDS. PMID: 27162691 [PubMed]
Source: Journal of Thoracic Disease - May 12, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Are acute coronary syndromes an ideal scenario for bioresorbable vascular scaffold implantation?
Authors: Moscarella E, Ielasi A, De Angelis MC, di Uccio FS, Cerrato E, De Rosa R, Campo G, Varricchio A Abstract Bioresorbable vascular scaffolds (BRS) represent the latest innovation in the field of interventional cardiology. BRS have recently been introduced in routine clinical practice and their use has progressively extended in everyday clinical practice. The BRS use appears theoretically attractive in patients presenting with acute coronary syndromes (ACS) as they are generally young with long life expectancy, thus possibly benefiting more of the so-called vascular reparative therapy. Furthermore, "culprit" l...
Source: Journal of Thoracic Disease - September 14, 2017 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Bioresorbable vascular scaffolds-time to vanish?
Authors: Arroyo D, Cook S, Puricel S Abstract The fully bioabsorbable vascular scaffold (BVS) has been developed to reduce late adverse events after coronary stenting such as device thrombosis. The device consists of polylactic acid, which is gradually absorbed within the first few years after its implantation. The initial experience with the device in low-risk patients presenting with simple lesions was satisfying and generated optimism among interventional cardiologists by promising better patient outcomes. However, the unrestricted use of the device in patients presenting with a higher baseline risk and more com...
Source: Journal of Thoracic Disease - June 15, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Bioresorbable vascular scaffolds in patients with acute myocardial infarction: a new step forward to optimized reperfusion?
Authors: Alfonso F, Cuesta J, Bastante T, Rivero F, García-Guimaraes M, Alvarado T, Benedicto A, Cortese B, Byrne R, Kastrati A Abstract Bioresorbable vascular scaffolds (BVS) represent a disruptive technology that has caused a new revolution in interventional cardiology. BVS appear to be particularly appealing in patients presenting with an acute myocardial infarction (MI). The available evidence on the value of BVS implantation in this challenging scenario is very promising but still limited. Results come from preliminary small observational studies, prospective registries that include a control group, and from ...
Source: Journal of Thoracic Disease - June 15, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Vascular approaches for transcatheter aortic valve implantation.
Authors: Pascual I, Carro A, Avanzas P, Hernández-Vaquero D, Díaz R, Rozado J, Lorca R, Martín M, Silva J, Morís C Abstract Transcatheter aortic valve implantation (TAVI) is a rapidly evolving therapeutic modality currently available for patients with severe aortic stenosis (AS) that are unsuitable for surgery because of technical/anatomical issues or high-estimated surgical risk. Transfemoral approach is the preferred TAVI delivery route when possible. Alternative non-transfemoral access options include transaortic, trans-subclavian and transapical access. Other approaches are also feasible (transcarotid, tran...
Source: Journal of Thoracic Disease - June 16, 2017 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Optical coherence tomography guidance during bioresorbable vascular scaffold implantation.
Authors: Secco GG, Verdoia M, Pistis G, De Luca G, Vercellino M, Audo A, Parisi R, Reale M, Ballestrero G, Marino PN, Di Mario C Abstract Bioresorbable vascular scaffold (BRS) represent a revolutionary concept in interventional cardiology. After initial enthusiasm, recent real world registries, including patients with increasing lesion complexity, reported not trivial rates of scaffold thrombosis (ScT). The importance of correct patients selection as well as technical aspects during BRS implantation procedures has been highlighted in several studies suggesting that the high rate of ScT might be related to uncorrect...
Source: Journal of Thoracic Disease - September 14, 2017 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Methods to assess bioresorbable vascular scaffold devices behaviour after implantation.
Authors: Pernigotti A, Moscarella E, Spitaleri G, Scardino C, Ishida K, Brugaletta S Abstract Bioresorbable vascular scaffolds (BRS) represent a novel approach for coronary revascularization offering several advantages as compared to current generation DES, potentially reducing rate of late adverse events and avoiding permanent vessel caging. Nevertheless, safety concerns have been raised for an increased risk of scaffold thrombosis (ScT) in both early and late phases, probably related to a suboptimal scaffold implantation. In this context, the use of different imaging methodologies has been strongly suggested in o...
Source: Journal of Thoracic Disease - September 14, 2017 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Occurrence and management of bioresorbable vascular scaffold failure in real-life studies.
Authors: Cortese B, Elwany M Abstract Bioresorbable vascular scaffold (BVS) has emerged as a new technology aiming at overcoming some drawbacks of the conventional metallic stent. In spite of the initial promising results, this technology stumbled upon numerous challenges, which were revealed in the real world studies. Thanks to real world trials and registries findings, our knowledge about the BVS has grown over time, thus we have understood on BVS behavior in various settings and formulated better implantation techniques. In this article, we will review the incidence of BVS failure in real world studies, its diff...
Source: Journal of Thoracic Disease - September 14, 2017 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Clinical outcomes following an initial experience with a novel powered vascular stapler in video-assisted thoracoscopic lobectomies: results of a Chinese multi-center study.
Conclusions: For VATS lobectomy, the PVS demonstrated a positive surgical effectiveness and value in cognitive and physical distress reduction. Complications following VATS lobectomy to treat NSCLC were generally low and as expected. Intraoperative complications were few and there were no postoperative complications related to the transection of the PA and PV during VATS lobectomy. Favorable results were reported on the surgeon satisfaction questionnaire regarding usability and surgeon stress. PMID: 31285890 [PubMed]
Source: Journal of Thoracic Disease - July 10, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Clinical significance of Charlson comorbidity index as a prognostic parameter for patients with acute or subacute idiopathic interstitial pneumonias and acute exacerbation of collagen vascular diseases-related interstitial pneumonia.
Conclusions: The composite scoring system including CCI, sex, and serum LDH could be a useful mortality prediction tool for patients with acute or subacute IIPs and AE of CVD-IP requiring steroid pulse therapy. PMID: 31372282 [PubMed]
Source: Journal of Thoracic Disease - August 4, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The powered vascular staple (PVS) versus conventional powered linier cutter (PLC) for the application of bronchial transection in thoracoscopic anatomic segmentectomy.
Conclusions: PVS is a smoother and easier instrument and has the same effectiveness and security as PLC. It leads to reduced operation difficulty and potential intraoperative complications. PMID: 31903253 [PubMed]
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research